ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
The Role of Surface Roughness on Membrane Leaflet Mobility in Supported Lipid Bilayers
Abstract: Interfacial membrane mimetics are a major theme within the neutron reflectometry group at ISIS. Within the group we offer a number of differing, biologically accurate, membrane models. Despite being the subject of several articles in the past the influence of the substrate on these biomimetics is often overlooked. However, we have noticed different leaflet flipping behaviour between Gram-nagtive membrane mimetics deposied on differentially cleaned silicon supports. We hypothesize that the differences are due to the level of surface influence on the bilayers being inversely correlated with the surface nano-roughness. Here we propoose to test this hypothesis and enable a better understanding of how to modulate substrate influence on supported lipid bilayers.
Experimenter: Mr Callum Houghton-Flory
Local Contact: Dr Luke Clifton
Experimenter: Professor Gail Preston
DOI: 10.5286/ISIS.E.RB2620003
ISIS Experiment Number: RB2620003
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2620003-1 | OFFSPEC | 09 October 2029 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Mr Callum Houghton-Flory et al; (2026): The Role of Surface Roughness on Membrane Leaflet Mobility in Supported Lipid Bilayers, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2620003
Data is released under the CC-BY-4.0 license.
