ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Water Incorporation into Stearate Salts in Hydrophobic Deep Eutectic Solvents
Abstract: Deep eutectic solvents (DES) are novel solvents comprised of naturally occurring compounds, which are non-toxic, sustainable and highly tuneable. They are mixtures which due to strong interactions between a hydrogen bond donor (HBD) and hydrogen bond acceptor (HBA), cause a melting point depression allowing them to be liquids at room temperature. DES based on carboxylic acids with menthol are hydrophobic, so they are used to extract hydrophobic actives from biomass and dissolve poorly water soluble therapeutics. These solutions are now being probed as components of formulation systems for delivery of such solutes. We are studying viscosity modification and self-assembly in these hydrophobic DES via the addition low concentrations of stearate salts, namely sodium, calcium and magnesium. This experiment plans to investigate the self assembly of stearate salts in menthol based DES in the presence of small amounts of water. This will be achieved by using deuterated stearate species and D2O in DES with varied d- or h-dodecanoic acid content to observing stearate assembly and the effects of water on clustering in the presence of the different salt cations.
Principal Investigator: Professor Karen Edler
Experimenter: Mr Carlo Carandente Coscia
Experimenter: Dr Glenn Coope
Experimenter: Mr Bradley Green
Local Contact: Dr Steven Parnell
DOI: 10.5286/ISIS.E.RB2520350
ISIS Experiment Number: RB2520350
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2520350-1 | LARMOR | 08 December 2028 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Karen Edler et al; (2025): Water Incorporation into Stearate Salts in Hydrophobic Deep Eutectic Solvents, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2520350
Data is released under the CC-BY-4.0 license.
