ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Neutron Reflection for the Air-Water Interface Structure of Binary Protein/ ranched-terpenoid Surfactant System
Abstract: Neutron reflection stands as a powerful technique for scrutinizing the microscopic structure of the air/water interface. This neutron reflection experiment aims to discern the co-adsorption behaviours of amino acid surfactants with branched hydrophobic chains and model protein at the air/water interface. By elucidating the relative content and positioning of both components in the interfacial layer, we aim to clarify the unique role of surfactant branched hydrophobic chains in the formation of protein-surfactant binary interface membranes. This elucidation will contribute to understanding the specific role of branched hydrophobic chains in preventing protein aggregation at the air/water interface, which is crucial in the drug-protein inactivation process in inhalation therapy. We request 4 days of neutron reflectometry beamtime on SURF to execute the proposed measurements. Chain-deuterated surfactants will be utilized to enhance sensitivity and resolution, which are indispensable for unravelling the structural intricacies in multicomponent surface systems.
Principal Investigator: Dr Peixun Li
Experimenter: Professor Quan Hao
Experimenter: Professor Yubin Ke
Experimenter: Dr Zi Wang
Experimenter: Dr Kun Ma
Experimenter: Dr Mario Campana
Experimenter: Dr Yao Chen
Local Contact: Dr John Webster
DOI: 10.5286/ISIS.E.RB2420489
ISIS Experiment Number: RB2420489
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2420489-1 | INTER | 15 December 2028 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Peixun Li et al; (2025): Neutron Reflection for the Air-Water Interface Structure of Binary Protein/ ranched-terpenoid Surfactant System, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2420489
Data is released under the CC-BY-4.0 license.
