ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Investigating Molecular Structure-Dependent Antimicrobial Behavior of Ethoxylated Quaternary Cationic Surfactants (EQCS) Using Neutron Reflectivity
Abstract: Surfactants are chemicals commonly found in cleaning products, cosmetics, and disinfectants. Some of them also kill bacteria, making them useful in healthcare and hygiene. In this project, we?re studying a special type of surfactant that can be adjusted at the molecular level to change how it behaves?specifically, how well it can kill harmful bacteria. We?ve designed a group of these surfactants with slightly different structures and are using a powerful scientific tool called neutron reflectivity to see how they interact with simple model membranes, similar to those found in bacteria. By using surfactants with a special "label" (deuterium) that neutrons can detect, we can precisely track where these molecules go and how they affect the membrane. The goal of this work is to understand what makes some of these surfactants more effective than others. With this knowledge, we hope to help create better and more targeted antibacterial products.
Principal Investigator: Dr Peixun Li
Experimenter: Mr kangcheng shen
Experimenter: Professor Jordan Petkov
Local Contact: Dr John Webster
Experimenter: Dr Bob Thomas
Experimenter: Professor Jeffery Penfold
Experimenter: Dr Kun Ma
Experimenter: Dr Yao Chen
DOI: 10.5286/ISIS.E.RB2520644
ISIS Experiment Number: RB2520644
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2520644-1 | OFFSPEC | 08 October 2028 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Peixun Li et al; (2025): Investigating Molecular Structure-Dependent Antimicrobial Behavior of Ethoxylated Quaternary Cationic Surfactants (EQCS) Using Neutron Reflectivity, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2520644
Data is released under the CC-BY-4.0 license.
