ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Radical oxidation of tear film at mammalian eye temperature ? development of dry eye disease.
Abstract: The proposal seeks to continue a series of experiments investigating the interaction between ambient atmospheric radicals and the aqueous lipid covered layer protecting mammalian eyes. Eyes are one of the most exposed mucosal interfaces on mammals and oxidation of the film may result in dry eye disease. We wish to investigate the change in morphology and amount of (1) partially deuterated proxy tear film mixtures and (2) the lipids harvested from human tear film with exposure to an atmospheric radical oxidant, OH radical. The work will be performed at mammalian eye temperature of 35°C. We will establish if the proxies are accurate and useful facsimiles or should not be used.
Principal Investigator: Professor Martin King
Experimenter: Miss Sophie Burr
Experimenter: Dr Katherine Thompson
Experimenter: Dr Rebecca Welbourn
Local Contact: Dr Maxmilian Skoda
Experimenter: Professor Philip Morgan
DOI: 10.5286/ISIS.E.RB2520469
ISIS Experiment Number: RB2520469
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2520469-1 | INTER | 10 October 2028 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Martin King et al; (2025): Radical oxidation of tear film at mammalian eye temperature ? development of dry eye disease., STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2520469
Data is released under the CC-BY-4.0 license.
