ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Changes in the water dynamics of lung cells (A549 cell line) induced by Tocilizumabe
Abstract: Through this proposal, we will achieve a much better understanding on the behaviour of water molecules of cells before and after being treated by the drug tocilizumabe (TCZ) either free or incorporated in the newly developed polymeric nanoparticles. Using TOSCA we will be able to uniquely correlate changes on the mobility of cellular water with the biological outcomes led by the drug.
Principal Investigator: Dr Fabio Formiga
Experimenter: Mrs Paloma Marques da Silva
Experimenter: Dr Jose Enedilton Medeiros Pereira
Experimenter: Professor Heloisa Nunes Bordallo
Local Contact: Dr Svemir Rudic
Experimenter: Dr Douglas Dourado
Experimenter: Mr Charalampos Tsekeridis
DOI: 10.5286/ISIS.E.RB2510169
ISIS Experiment Number: RB2510169
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2510169-1 | TOSCA | 05 May 2028 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Fabio Formiga et al; (2025): Changes in the water dynamics of lung cells (A549 cell line) induced by Tocilizumabe, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2510169
Data is released under the CC-BY-4.0 license.
