ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Radical oxidation of tear film ? development of dry eye disease.
Abstract: The proposal seeks to continue a series of experiments investigating the interaction between atmospheric radicals and the aqueous lipid covered layer protecting mammalian eyes. Eyes are one of the most exposed mucosal interfaces on mammals and oxidation of the film may result in dry eye disease. We wish to demonstrate that the morphology of partially deuterated proxy tear film mixtures changes with exposure to an atmospheric radical oxidant, OH radical. The work will also continue to test if human tear film harvested from the experimenters and placed at the air-water interface has enough contrast to be visible on INTER.
Principal Investigator: Professor Martin King
Experimenter: Dr Katherine Thompson
Local Contact: Dr Maxmilian Skoda
Experimenter: Dr Rebecca Welbourn
Experimenter: Miss Sophie Burr
Experimenter: Professor Philip Morgan
DOI: 10.5286/ISIS.E.RB2510649
ISIS Experiment Number: RB2510649
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2510649-1 | INTER | 23 May 2028 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Martin King et al; (2025): Radical oxidation of tear film ? development of dry eye disease., STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2510649
Data is released under the CC-BY-4.0 license.
