ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Characterising XopR during membrane interactions
Abstract: The role of Liquid-liquid phase separation (LLPS) in biology is increasingly recognised. Actin remodelling has been found to involve LLPS, which likely acts to upregulate critical proteins and adjust their activity. Intrinsically disordered protein XopR, which undergoes LLPS at a pH of 7.4, has been found to trigger actin remodelling. Previous NR work performed at ISIS and ANSTO have shown the effect of XoPR on a variety of dueterated lipid membranes in both LLPS and dilute conditions. Here, neutron reflectometry will be used with dueterated XopR to isolated the structrue of XopR on the surface of the membrane.
Principal Investigator: Professor Marité Cárdenas Gómez
Experimenter: Dr Claire Buchanan
Local Contact: Dr Oleksandr Tomchuk
Experimenter: Mr Jon Altuna
Experimenter: Ms Soto Noelia
DOI: 10.5286/ISIS.E.RB2420136
ISIS Experiment Number: RB2420136
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2420136-1 | INTER | 26 November 2027 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Marité Cárdenas Gómez et al; (2024): Characterising XopR during membrane interactions, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2420136
Data is released under the CC-BY-4.0 license.
