ISIS Neutron and Muon Source Data Journal

Applications of muon in cancer research

Abstract: Even though there are several existing methods for detection of molecular oxygen in tissues, new noninvasive methods are needed to measure the presence of hypoxia, its extent and spatial distribution within tumor. Using quantum beam of muon, a new noninvasive method to observe the three-dimensional images of concentration of oxygen in tissues is proposed here. We have already confirmed the reliability and sensitivity of the proposed method to low oxygen concentration in water and dilute aqueous biological solutions. Before applying to real biosamples and applications towards clinical/medical purposes for tumor/cancer diagnosis/treatment, we would like to perform systematic study in different hemoglobin (Hb) concentrations (up to physiological concentration) in water, blood plasma, high Hb in blood plasma and inhomogeneous system of oxygen and Hb in in-vivo type experimental set-up.

Experimenter: Dr Amba Datt Pant
Experimenter: Dr Katsuhiko Ishida
Experimenter: Mr ROSHAN PUDASAINI
Experimenter: Dr Akihiro Koda
Experimenter: Professor Kanetada Nagamine
Experimenter: Dr Raja Adhikari
Experimenter: Professor Koichiro Shimomura
Experimenter: Professor Jerome Schultz
Local Contact: Dr Stephen Cottrell

DOI: 10.5286/ISIS.E.RB2270002

ISIS Experiment Number: RB2270002

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Amba Datt Pant et al; (2024): Applications of muon in cancer research, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2270002

Data is released under the CC-BY-4.0 license.