ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Interaction between Cationic Lipopeptides and Models of Gram-Negative Bacterial Membranes Studied by Neutron Reflection
Abstract: A group of designed lipopeptides with 4 amino acids have displayed large differences in antimicrobial efficacy and biocompatibility, as well as in secondary structures upon membrane binding. Neutron reflection is about the only method that could help reveal how these lipopeptides attack inner and outer membranes of Gram-negative bacteria from the established membrane models for bacteria, thus helping explain their anti-microbial actions. This work is part of PhD research by Tianhao Ge and constitutes an important aspect of our design and development of effective antimicrobial peptides.
Principal Investigator: Professor Jian Lu
Experimenter: Miss Tianhao Ge
Local Contact: Dr Maxmilian Skoda
Experimenter: Miss Yingyu Wang
Experimenter: Dr Mingrui Liao
Experimenter: Miss Anna Stephens
Experimenter: Mr Shilin Deng
Experimenter: Mr kangcheng shen
DOI: 10.5286/ISIS.E.RB2320047
ISIS Experiment Number: RB2320047
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2320047-1 | INTER | 09 March 2027 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jian Lu et al; (2024): Interaction between Cationic Lipopeptides and Models of Gram-Negative Bacterial Membranes Studied by Neutron Reflection, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2320047
Data is released under the CC-BY-4.0 license.
