ISIS Neutron and Muon Source Data Journal

Correlating SANS and SESANS to study membrane and morphology changes in Bacteria (continuation)

Abstract: Bacteria and the infections they cause are a huge problem due to the advent of antimicrobial resistance (AMR). To kill bacteria with greater efficacy and limit the rate at which AMR develops we must better understand the nanostructures bacteria have developed to protect themselves. To do this requires us to study the bacteria outer cell walls that provide them with such amazing mechanical integrity. We have recently shown that we can measure changes in the size and volume of bacteria using SESANS as well as changes in the bacterial celll wall nanostructure using SANS. In this new proposal we plan to probe the kinetics of this process along the bacterial growth curve and using different exposure times to the antibiotic methicllin.

Principal Investigator: Dr Andrew Parnell
Local Contact: Dr Gregory Smith
Local Contact: Dr Robert Dalgliesh
Experimenter: Miss Victoria Jayne Lloyd
Experimenter: Dr Steven Parnell
Experimenter: Professor Jamie Hobbs
Experimenter: Dr Laia Pasquina-Lemonche
Experimenter: Dr Thomas Catley

DOI: 10.5286/ISIS.E.RB2320228

ISIS Experiment Number: RB2320228

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Andrew Parnell et al; (2024): Correlating SANS and SESANS to study membrane and morphology changes in Bacteria (continuation), STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2320228

Data is released under the CC-BY-4.0 license.