ISIS Neutron and Muon Source Data Journal

Interactions between membranes and nano-ions: Nanostructural insights from SANS

Abstract: Nano-ions such as polyoxometalates (POMs), boron clusters and hydrophobic ions (Fig.2), are nanometric ionic molecules with unique architecture and super-chaotropic properties, that is, they can disrupt hydrogen bonding, penetrate hydrophobic cavities, and bind to non-ionic sites or molecules. This implies that they could potentially mediate effective structural disruption in cell membranes. However, little is known how the nano-ions would affect the mechanism of membrane fusion, fundamentally relevant to nanotoxicity and specifically to their conjectured use in personal care products and as future delivery vectors. Here, we propose a small-angle neutron scattering (SANS) study to examine the structural changes in liposomes mediated by nano-ions, as a function of lipid composition, type of nano-ions, concentrations, and temperature.

Experimenter: Mr Matteo Fois
Experimenter: Miss Charlotte Kenton
Experimenter: Professor Wuge Briscoe
Experimenter: Dr Sarah Rogers
Local Contact: Dr Gregory Smith
Experimenter: Miss Xueying Guo
Experimenter: Dr Magdalena Wlodek
Experimenter: Miss Sofia Rogers Ruiz

DOI: 10.5286/ISIS.E.RB2310378

ISIS Experiment Number: RB2310378

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Mr Matteo Fois et al; (2023): Interactions between membranes and nano-ions: Nanostructural insights from SANS, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2310378

Data is released under the CC-BY-4.0 license.