ISIS Neutron and Muon Source Data Journal

Characterization of the behavior of hydrophobic domain in hydrogel on hydrophobic and hydrophilic interfaces

Abstract: Biocompatible hydrogels are of central importance for many applications in the field of life science. A central point in all such applications is their adhesion to a solid surface, which is typically achieved by the application of soft pressure. We have developed such a hydrogel that contains cholic acid groups and whose adhesion underwater becomes stronger with increased content of cholic acid. Assumed is here the formation of hydrophobic domains of the cholic acid moieties at the interface that should also depend on the extent of hydrophobicity of the substrate. Neutron reflectometry in D2O shall be done in order to see how the hydrogel structure at the interface changes as a function of applied pressure and the content of cholic acid in the hydrogel. This is essential to understand macroscopic adhesion in terms of mesoscopic structure and thereby rationalize molecular hydrogel design.

Principal Investigator: Professor Michael Gradzielski
Experimenter: Miss Hanna Rulff
Local Contact: Dr Rebecca Welbourn
Experimenter: Mr Robert Franz Schmidt
Experimenter: Ms Yining Sun

DOI: 10.5286/ISIS.E.RB2220508

ISIS Experiment Number: RB2220508

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Michael Gradzielski et al; (2022): Characterization of the behavior of hydrophobic domain in hydrogel on hydrophobic and hydrophilic interfaces, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2220508

Data is released under the CC-BY-4.0 license.