ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Influence of polarisation analysis on buffer subtraction in biology
Abstract: Protein dynamics play a vital role in biology. Quasi elastic neutron scattering is an ideal method to access these, data analysis is performed based on the assumption that the scattering spectrum is incoherent. To observe the full range of dynamical changes the proteins need to be observed in solution. This solution is usually a fully deuterated buffer, while the protein remains deuterated. It is generally assumed that while the buffer leads to a coherent contribution, which can be taken into account during data analysis by subtracting the buffer contribution from the sample spectrum. Polarised QENS experiments on LET allow for the coherent and incoherent contributions to be separated. By comparing the results from the polarised QENS experiment and the standard analysis method from unpolarised QENS it will be possible to experimentally check the current approach to data analysis.
Local Contact: Dr Mona Sarter
DOI: 10.5286/ISIS.E.RB2220749
ISIS Experiment Number: RB2220749
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2220749-1 | LET | 07 October 2025 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Mona Sarter; (2022): Influence of polarisation analysis on buffer subtraction in biology, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2220749
Data is released under the CC-BY-4.0 license.
