ISIS Neutron and Muon Source Data Journal

Distance Tuning Floating Membranes Through pH Control

Abstract: We have developed a self-assembled floating bilayer sample systems for use as a membrane biomimetic. These are comprised of fluid phase phospholipid bilayers which float adjacent to carboxyl terminated oligo-ethylene-glycol self-assembled monolayers (COOH-OEG-SAMs). We found that changing the solution salt conditions modifies the distance between the bilayer and the SAM. Simulation studies suggest cation bridging between the membrane and the SAM as the cause of this novel effect. Here we wish to use pH to modifying the membrane/SAM surface charge and measure changes in membrane-to-SAM distance as a result of this. This will provide further evidence on the cause of this novel distance tuning effect and allow us to gain a fuller understanding of this biotechnologically relivant sample system.

Experimenter: Mrs Laura John
Experimenter: Professor Mark Sansom
Experimenter: Professor Gail Preston
Local Contact: Dr Luke Clifton

DOI: 10.5286/ISIS.E.RB2220393

ISIS Experiment Number: RB2220393

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Mrs Laura John et al; (2022): Distance Tuning Floating Membranes Through pH Control, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2220393

Data is released under the CC-BY-4.0 license.