ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Correlating penetration and conformation of HIV fusion peptide with composition of model mammalian cell membranes
Abstract: In this proposal we aim to perform Neutron measurements on phase-segregated cholesterolcontaining supported lipid bilayers of various compositions involving charged and uncharged lipids to study the interaction with viral fusion peptides at different concentrations. This study shall throw light regarding how different peptide concentrations in aggregated state fuse with heterogeneous membranes having lipid rafts, the extent of peptide penetration, their possible conformation states and the role of charge in this fusion process.
Principal Investigator: Professor Jaydeep Basu
Experimenter: Mr Anurag Chaudhury
Local Contact: Dr Maxmilian Skoda
Experimenter: Mr Shovon Swarnakar
DOI: 10.5286/ISIS.E.RB2220572
ISIS Experiment Number: RB2220572
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2220572-1 | OFFSPEC | 27 September 2025 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jaydeep Basu et al; (2023): Correlating penetration and conformation of HIV fusion peptide with composition of model mammalian cell membranes, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2220572
Data is released under the CC-BY-4.0 license.
