This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Understanding the structure and phytochemical loading of bile salt containing liposomes
Abstract: The information about the morphology of colloidal systems plays an essential role in controlling the biological fate and bioavailability of cargo loaded systems in the gastrointestinal tract. Recently there has been interest in the incorporation of bile salts (BSs) into phospholipid vesicles to enhance the bioavailability of phytochemicals with the modification of the structure. BSs containing systems are already utilized in the pharmaceutical industry as a delivery vehicles, however, they have not been employed for the encapsulation of phytochemicals in the food industry.Resveratrol (as a model phytochemical) loaded phospholipid/BSs system will be used to investigate structures and interactions, controlling the fate of the system in the gastrointestinal tract, and explore the adaptability of the system into the food formulations.
Principal Investigator: Dr Arwen Tyler
Local Contact: Dr James Doutch
Experimenter: Miss Emma Thompson
Experimenter: Miss Aygul Can
Experimenter: Miss Niamh O'Donoghue
DOI: 10.5286/ISIS.E.RB2210350
ISIS Experiment Number: RB2210350
Part DOI | Instrument | Public release date | Download Link |
---|---|---|---|
10.5286/ISIS.E.RB2210350-1 | SANS2D | 06 July 2025 | Download |
- | SANS2D | 16 December 2025 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Arwen Tyler et al; (2022): Understanding the structure and phytochemical loading of bile salt containing liposomes, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2210350
Data is released under the CC-BY-4.0 license.