ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Spontaneous liposome formation in the presence of amphiphilic drugs
Abstract: Biological membranes and their interactions are naturally of the utmost importance for all living entities. Amphiphilic drugs interact and self-assemble with phospholipids and are expected to influence properties related to pharmacological activity and toxicity. For instance, they are expected to play a crucial role regarding specific interactions with receptor proteins, hemolytic degradation, as well as function as a drug delivery agent in release mechanisms and transport of drug molecules across cell membranes. The main purpose of the experiment is to determine the distribution of drug surfactants in spontaneously formed drug/phospholipid liposomes by means of employing hydrated as well as a deuterated phospholipid in a contrast match study.
Principal Investigator: Dr Lars Magnus Angantyr Bergström
Experimenter: Dr Franz Adlmann
Local Contact: Dr James Doutch
Experimenter: Mr Vahid Forooqi Motlaq
DOI: 10.5286/ISIS.E.RB2010209
ISIS Experiment Number: RB2010209
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB2010209-1 | ZOOM | 19 November 2023 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Lars Magnus Angantyr Bergström et al; (2020): Spontaneous liposome formation in the presence of amphiphilic drugs, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2010209
Data is released under the CC-BY-4.0 license.
