ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Molecular recognition in the LysM/Carbohydrate system
Abstract: Molecular recognition of carbohydrates regulates many essential biological processes in living organisms. One carbohydrate binding module (CBM) conserved across all kingdoms is LysM: which is present in bacterial extra-cellular proteins including hydrolases, adhesins and virulence factors such as Protein A from Staphylococcus aureus. LysM modules consist of 43–50 amino acids that adopt a highly conserved beta-alpha-alpha-beta fold, with particularly high sequence conservation in the first 16 residues1,28,17. Prokaryotic LysM modules bind peptidoglycan, the main component of the bacterial cell wall, made of alternating N-acetylglucosamine (GlcNAc) and Nacetylmuramic acid (MurNAc) residues, substituted by short peptide stems
Principal Investigator: Dr David Scott
Experimenter: Dr Nicola Galley
Local Contact: Dr James Doutch
Experimenter: Professor Mike Williamson
Local Contact: Dr Leide Cavalcanti
DOI: 10.5286/ISIS.E.RB1920254
ISIS Experiment Number: RB1920254
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB1920254-1 | ZOOM | 25 May 2024 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr David Scott et al; (2021): Molecular recognition in the LysM/Carbohydrate system, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920254
Data is released under the CC-BY-4.0 license.
