ISIS Neutron and Muon Source Data Journal

Investigation of Folded Globular Maltose Binding Protein Based Hydrogels

Abstract: We have developed a new model to describe the structural architecture of hydrogels composed of cross-linked maltose binding proteins (MBP), supported by multiple techniques including SANS. We suggest that these gels are constituent of large fractal-like aggregates of folded MBP protein that are linked together by unfolded protein. In this new SANS proposal, we aim to determine the size and structure of the fractal aggregates present in MBP based hydrogels as a function of protein volume fraction. These experiments are crucial to validating our hypothesis of the structure of MBP hydrogels, which will provide insight into the structural parameters of folded protein hydrogels and assist the development of design rules for hydrogels with specific properties.

Principal Investigator: Professor Lorna Dougan
Experimenter: Dr Matthew Hughes
Local Contact: Dr Najet Mahmoudi
Experimenter: Miss Sophie Cussons
Experimenter: Ms Kalila Cook

DOI: 10.5286/ISIS.E.RB1920289

ISIS Experiment Number: RB1920289

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Lorna Dougan et al; (2019): Investigation of Folded Globular Maltose Binding Protein Based Hydrogels, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920289

Data is released under the CC-BY-4.0 license.