ISIS Neutron and Muon Source Data Journal

Dynamic transition of Poly(ethylene glycol) with or without the solvation water

Abstract: Water is the source of life, but the effects of hydration water on the dynamics and function of biological and bio-compatible macromolecules are still full of debates. Chen et al. found a dynamic transition of the solvation water at about 220 K, and claimed that such a liquid-liquid transition of water command the dynamic and function of the proteins. However, Hong and colleagues found out that dry perdeuterated protein also experience a dynamic transition at about 200 K by quasi-elastic neutron scattering. To clarify the problem, a direct observation of the dynamics of the hydration layer about macromolecule in the transition process is crucial. Here, we propose quasi-elastic neutron scattering of dry Poly(ethylene glycol) (PEG) and PEG solvated with a single layer of water bellow and up the liquid-liquid transition of confined water at about 200 K.

Principal Investigator: Dr He Cheng
Local Contact: Dr Victoria Garcia Sakai
Experimenter: Mr SONGWEN XIAO
Experimenter: Dr Taisen Zuo
Experimenter: Dr Guisheng Jiao
Experimenter: Dr CHANGLI MA
Experimenter: Mr XIONG LIN

DOI: 10.5286/ISIS.E.RB1920340

ISIS Experiment Number: RB1920340

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr He Cheng et al; (2019): Dynamic transition of Poly(ethylene glycol) with or without the solvation water , STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920340

Data is released under the CC-BY-4.0 license.