ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Structural evidence from SANS on self-assembly of antimicrobial lipopeptides and their interactions with small unilamellar vesicles
Abstract: Previous studies have demonstrated that the de novo designed antimicrobial lipopeptides can self-assemble to beta-sheet nanofibers, but can transform to alpha-helical monomers once interacting with the anionic bacterial membranes. Following the above work, we propose to investigate the structural evidence of the self-assembly of lipopeptides by using small angel neutron scattering (SANS) to characterise the nanofibers before and after interactions with small unilamellar vesicles (SUVs). This work will provide valuable molecular insight of modes of action of the the lipopeptides to different model membranes.
Principal Investigator: Professor Jian Lu
Experimenter: Mr Haoning Gong
Local Contact: Dr Steve King
Experimenter: Dr Arwel Hughes
Experimenter: Dr Luke Clifton
Experimenter: Dr Zongyi Li
Experimenter: Mr KE FA
DOI: 10.5286/ISIS.E.RB1920157
ISIS Experiment Number: RB1920157
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB1920157-1 | LOQ | 24 November 2022 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jian Lu et al; (2019): Structural evidence from SANS on self-assembly of antimicrobial lipopeptides and their interactions with small unilamellar vesicles, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920157
Data is released under the CC-BY-4.0 license.
