ISIS Neutron and Muon Source Data Journal

Investigation of membrane polymer complex using SANS

Abstract: The interaction between lipid vesicles and macromolecules, like polymers is of intense importance from both theoretical and practical point of view. On one hand lipid vesicles can successfully mimic cell membrane on the other hand only on understanding the effect of polymer-lipid interaction one can control the mechanism and degree of polymer encapsulation in passive (no active chemical trigger) in a drug delivery (cargo). But such fine-tuning is only possible on changing the hydrophobic: hydrophilic balance (H) and number density (n) of the polymer. The effect of which can be directly visible in the change in the structure of the lipid-bilayer. Therefore, here we aim at understanding the change in membrane structure caused by such membrane-polymer interaction. The finding may represent an important aspect for further understanding of the effects related to the polymer biocompatibility.

Principal Investigator: Dr Sudipta Gupta
Experimenter: Professor Gerald Schneider
Local Contact: Dr Leide Cavalcanti
Experimenter: Miss Judith De Mel

DOI: 10.5286/ISIS.E.RB1920546

ISIS Experiment Number: RB1920546

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Sudipta Gupta et al; (2019): Investigation of membrane polymer complex using SANS, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920546

Data is released under the CC-BY-4.0 license.