ISIS Neutron and Muon Source Data Journal

Self-assembled Floating Lipid Bilayers: What Forces Are Causing the Bilayer to Surface Distance Control?

Abstract: Recently (RB19100102) we have discovered that floating bilayers composed of fluid phase lipids can be produced by deposited vesicles onto charge modified oligo(ethylene glycol)coated gold surfaces. Changing the solution NaCl concentration was found to cause the membrane to surface distance to increase. This effect is likely related to one or a combination of two phenomena. Either secondary hydration forces arising from the binding of hydrated cations to the charged SAM surface or a change in membrane surface charge due to head group ion interactions. We plan to compare the change in bilayer to surface distance using four differing Salt solutions (NaCl, LiCl, NaBr and LiBr) to determine which mechanism is controlling the changes in membrane to surface distance in these new functional membrane mimetics.

Principal Investigator: Dr Luke Clifton
Experimenter: Professor Mark Sansom
Experimenter: Dr Maxmilian Skoda
Experimenter: Professor Gail Preston
Experimenter: Mrs Laura John
Experimenter: Dr Andrew McCluskey
Experimenter: Dr Andreas Haahr Larsen

DOI: 10.5286/ISIS.E.RB1920026

ISIS Experiment Number: RB1920026

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Luke Clifton et al; (2019): Self-assembled Floating Lipid Bilayers: What Forces Are Causing the Bilayer to Surface Distance Control?, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920026

Data is released under the CC-BY-4.0 license.