ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Interactions of de Novo Designed Antimicrobial Lipopeptides with Model Leaflets of Inner Microbial Membranes – A NR study
Abstract: In this work, we propose to exploit the unique capability of neutron reflection (NR) to study the structural changes of multi-component lipid monolayer models mimicking bacterial membranes upon their exposure to de novo designed ultrashort antimicrobial lipopeptides, focusing on unravelling their unusual mechanism of action. NR is the only technique that can determine the amount and distribution of these represent AMPs once adsorbed. We request 3 days on INTER using the event mode to complete this work.
Principal Investigator: Professor Jian Lu
Experimenter: Dr Zongyi Li
Experimenter: Dr Lisa Pan
Local Contact: Dr Mario Campana
Experimenter: Mr KE FA
Experimenter: Mr Sean Ruane
Experimenter: Dr Mingrui Liao
Experimenter: Mr Huayang Liu
DOI: 10.5286/ISIS.E.RB1920156
ISIS Experiment Number: RB1920156
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.RB1920156-1 | SURF | 09 October 2022 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jian Lu et al; (2019): Interactions of de Novo Designed Antimicrobial Lipopeptides with Model Leaflets of Inner Microbial Membranes – A NR study, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920156
Data is released under the CC-BY-4.0 license.
