This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Influence of Alkyl Chain Fluidity on the Membrane Binding Activity of Cationic Surfactants
Abstract: Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improves patient compliance and can provide a release for long periods of time. One of the greatest challenges for transdermal delivery is that only a limited number of drugs can penetrate the skin by this route. This proposal will focus on the interaction between the model membrane and surfactants, and try to understand the influence of surfactant fluidity. This work may contribute to the surfactant-based transdermal drug delivery system in the future.
Principal Investigator: Dr Yao Chen
Experimenter: Mr Zi Wang
Experimenter: Dr Kun Ma
Experimenter: Dr Peixun Li
Experimenter: Dr John Webster
Experimenter: Dr Mario Campana
DOI: 10.5286/ISIS.E.RB1920681
ISIS Experiment Number: RB1920681
Part DOI | Instrument | Public release date | Download Link |
---|---|---|---|
10.5286/ISIS.E.RB1920681-1 | SURF | 12 March 2023 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Yao Chen et al; (2019): Influence of Alkyl Chain Fluidity on the Membrane Binding Activity of Cationic Surfactants, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920681
Data is released under the CC-BY-4.0 license.