This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Role of Antifreeze Glycoproteins (AFGPs) in Preventing Ice-formation
Abstract: Antifreeze glycoproteins (AFGPs) are an important biological complex and a novel set of proteins that can prohibit the formation of ice. The AFGPs can be extracted from the blood plasma of Antarctic notothenioids and northern cod. The configuration change in amino acids or (sub-) domain inside a protein is often responsible for its activity, which is closely connected to the thermal hysteresis (TH) of AFGP, a unique characteristic of this family of protein. In this proposed research we are going to explore how AFGPs can prevent ice formation in D2O and H2O solutions by studying the dynamics of its hydration water and bulk water in the solution in the time range of several tens of picoseconds and up to few nm using QENS at IRIS.
Principal Investigator: Professor Rosie Chu
Local Contact: Dr Victoria Garcia Sakai
Experimenter: Mr SHENGKAI ZHANG
Experimenter: Miss jingjing Han
Experimenter: Mr Xudong Gu
Experimenter: Mr Zhixin Wang
Experimenter: Dr Qun Wan
DOI: 10.5286/ISIS.E.RB1920374
ISIS Experiment Number: RB1920374
Part DOI | Instrument | Public release date | Download Link |
---|---|---|---|
10.5286/ISIS.E.RB1920374-1 | IRIS | 11 October 2022 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Rosie Chu et al; (2019): Role of Antifreeze Glycoproteins (AFGPs) in Preventing Ice-formation, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920374