ISIS Neutron and Muon Source Data Journal

A Contrast Variation SANS Study of Biocatalytic Peptide Self-Assembly

Abstract: The solution nanostructure of peptide assemblies with catalytic properties will be investigated using small-angle neutron scattering. This is a method to probe the structure and dimensions of nanoscale structures such as micelles and fibres formed by self-assembled molecules including peptides and molecules with attached lipid chains. By varying the composition of water and deuterium oxide (which is an isotopically labelled version of water, also known as heavy water) the neutron scattering power of the solution can be varied in order to highlight particular features of the molecule within the aggregates. We will use this method investigate the detailed inner structure of micelle and fibre self-assemblies formed by lipidated peptides with short peptide groups that have been shown to have activity as catalysts.

Principal Investigator: Professor Ian Hamley
Experimenter: Miss Juliane Pelin
Experimenter: Dr Charlotte Jennifer Chante Edwards-Gayle
Experimenter: Dr Valeria Castelletto
Local Contact: Dr Adam Washington

DOI: 10.5286/ISIS.E.RB1910005

ISIS Experiment Number: RB1910005

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Ian Hamley et al; (2019): A Contrast Variation SANS Study of Biocatalytic Peptide Self-Assembly, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1910005

Data is released under the CC-BY-4.0 license.