ISIS Neutron and Muon Source Data Journal

Probing chiral interactions in aqueous amino acid deriving polymers

Abstract: Sodium deoxycholate (NaDC) is a low molecular weight gelator, widely known as one of the components of bile salts. Above a specific concentration, NaDC is able to form pH dependent chiral micelles. Whereas an increasing number of articles is dealing with NaDC hydrogel properties, an in-depth understanding of the chiral recognition between NaDC and enantiomeric polymers is still missing. In this proposal we wish to increase our knowledge on the ability of NaDC to selectively interact with chiral polymers, namely L- and D-ARGO7. These biobased polymers are synthesised by the polyaddition of L- or D-aminoacids to methylenebisacrylamide. In water, they showed conformations reminescent of the protein hairpin motif. Of interest is how NaDC micelles conformation changes upon addition of the charged polymer, and how the structure is differently affected by its D- or L- form.

Principal Investigator: Professor Peter Griffiths
Experimenter: Professor Dame Elisabetta Ranucci
Experimenter: Miss Federica Lazzari
Experimenter: Dr Jenny Alongi
Experimenter: Dr Omar Mansour
Local Contact: Dr Robert Dalgliesh

DOI: 10.5286/ISIS.E.RB1910089

ISIS Experiment Number: RB1910089

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Peter Griffiths et al; (2019): Probing chiral interactions in aqueous amino acid deriving polymers , STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1910089

Data is released under the CC-BY-4.0 license.