ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Charged nanogels and their ability to penetrate model lipid membranes
Abstract: Drug delivery through the skin is an important route for administration of therapeutic agents. However, the outermost layer of the skin, the stratum corneum provides a formidable barrier to dermal absorption and penetration of drugs or therapeutic agents. In this proposal we aim to investigate the interaction of charged cross-linked polymeric nanogels with a ceramide lipid multilayers and mixed lipid multilayers of ceramide lipid/cholesterol/fatty acid, designed to mimic the lipid organization of the human skin.
Principal Investigator: Dr Ali Zarbakhsh
Local Contact: Dr Mario Campana
Experimenter: Dr Katarzyna Zielinska
Experimenter: Dr John Webster
Experimenter: Dr Marina Resmini
DOI: 10.5286/ISIS.E.RB1520134
ISIS Experiment Number: RB1520134
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.63528039 | INTER | 02 October 2018 | Download |
| 10.5286/ISIS.E.66586416 | SURF | 16 October 2018 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Ali Zarbakhsh et al; (2015): Charged nanogels and their ability to penetrate model lipid membranes, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1520134
Data is released under the CC-BY-4.0 license.
