ISIS Neutron and Muon Source Data Journal

This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.


Stretching elastic

Abstract: In all mammals, tissue elasticity is conveyed by elastin. Elastin is an essential extracellular matrix protein found within arteries, skin, lungs and elastic cartilage. Elastin's responses to systole and diastole are needed to maintain and regulate blood pressure during and between heartbeats. Tropoelastin is the soluble precursor of elastin and is the most elastic biomaterial known. In solution Tropoelastin is an asymmetric molecule about 20nnm in length with a foot protubance which contains the cell interaction motif. However, little is known about how this protein may deform under shear or extension stresses. By combining SANS with in-situ flow fields, we will determine this response through the visualization of changes in the orientation, shape and size of the protein induced by these flow fields.

Principal Investigator: Dr Ann Terry
Experimenter: Professor Clair Baldock
Experimenter: Dr Ian Tucker
Experimenter: Professor Tony Weiss
Local Contact: Dr Sarah Rogers
Experimenter: Mr Michael Lockhart

DOI: 10.5286/ISIS.E.RB1510616

ISIS Experiment Number: RB1510616

Part DOI Instrument Public release date Download Link
10.5286/ISIS.E.63525776 SANS2D 10 September 2018 Download

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Ann Terry et al; (2015): Stretching elastic, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510616

Data is released under the CC-BY-4.0 license.



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