ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Solvent and drug diffusion in supramolecular gels
Abstract: This proposal addresses issues related to understanding drug diffusion in supramoleculargels with view at fundamental pharmacological questions for drug delivery. Preliminary data from IN6 (ILL) and LET indicate a small but systematic difference in the diffusion of the solvent withinsupramolecular gel samples compared to the diffusion in the corresponding pure solventsamples. We hypothesize that this trend is due to soft micro-confinement effects and we now propose to verify this trend by measuring a second solvent system on LET. In addition, we wish to measure new samples withthe model drug ibuprofen sodium load. The results from these experiment will directly influence the understanding of supramolecular gels as drug delivery vehicles.
Principal Investigator: Dr Katharina Edkins
Experimenter: Dr Tilo Seydel
Experimenter: Professor Jonathan Steed
Local Contact: Dr Rob Bewley
DOI: 10.5286/ISIS.E.RB1510163
ISIS Experiment Number: RB1510163
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.63524067 | LET | 22 September 2018 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Katharina Edkins et al; (2015): Solvent and drug diffusion in supramolecular gels, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510163
Data is released under the CC-BY-4.0 license.
