ISIS Neutron and Muon Source Data Journal

The role of biogenic amines in lipopeptide biofilm formation

Abstract: Pore forming lipopeptides, such as Tolaasin, are produced by pathogenic mushroom bacteria, and are implicated in diseases such as ¿brown blotch¿ disease. They have potential applications as anti-fungal, anti-bacterial, anti-viral molecules, and as anti-cancer agents. Biogenic agents, such as octopamine, are observed to enhance or suppress biofilm formation in the tolassin expressing bacteria, such as Pseudomonas fluorescens, with significant bio-medical implications. We propose to use NR to investigate the surface adsorption properties of tolaasin in the presence of octopamine, in order to understand the role of their surface adsorption and interaction on the mechanism of tolaasin biofilm control.

Principal Investigator: Professor Jeffery Penfold
Experimenter: Dr Bob Thomas
Experimenter: Dr Peixun Li
Experimenter: Dr Filip Ciesielski
Experimenter: Dr Peixun Li
Experimenter: Professor Gail Preston
Local Contact: Dr John Webster

DOI: 10.5286/ISIS.E.RB1310022

ISIS Experiment Number: RB1310022

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Jeffery Penfold et al; (2013): The role of biogenic amines in lipopeptide biofilm formation, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1310022

Data is released under the CC-BY-4.0 license.