ISIS Neutron and Muon Source Data Journal

This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.


Thermal fluctuations of cold shock proteins from different flavours of extremophilic organisms

Abstract: Extremophiles are organisms which survive and thrive in extreme environments. The proteins from extremophilic organisms have received considerable attention as they are structurally stable and functionally active under extreme physical and chemical conditions. Our goal is to obtain the design principles which accurately describe the interactions which allow extremophilic proteins to be stable and flexible at extreme temperatures. We wish to combine neutron scattering experiments with a range of other experimental and computational tools to provide a complete picture of the protein's structure and dynamics. This will provide fundamental insights into the mechanisms of adaptation of extremophile organisms, in addition to providing a foundation for the development of an understanding of biological molecules that can be exploited in synthetic biology, industry and bionanotechnology.

Principal Investigator: Professor Lorna Dougan
Experimenter: Mr Dominic Loraine
Experimenter: Mr David West
Local Contact: Dr Victoria Garcia Sakai
Experimenter: Mr Michael Wilson
Experimenter: Mr Samuel Lenton

DOI: 10.5286/ISIS.E.RB1520240

ISIS Experiment Number: RB1520240

Part DOI Instrument Public release date Download Link
10.5286/ISIS.E.67769105 IRIS 16 November 2018 Download

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Lorna Dougan et al; (2015): Thermal fluctuations of cold shock proteins from different flavours of extremophilic organisms, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1520240

Data is released under the CC-BY-4.0 license.



UKRI


Science and Technology Facilities Council Switchboard: 01793 442000