ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Nanosuspsomicroemulsions: nanosuspension stabilty
Abstract: At Kings College London we have recently developed a novel combination formulation, a nanosuspsomicroemulsion (NSME), comprising of a microemulsion (ME) containing one drug and polymer and/or surfactant coated nanoparticles (NS) of a second drug to allow co-administration of two poorly water soluble drugs. The aim of the study is to use SANS in combination with contrast variation to determine the size (in situ) of drug NS contained in the NSME. By contrast matching the ME droplets it will be possible to mask their presence enabling the size and stability of the NP to be determined in situ, something not readily possible by any other technique. The results of the study will be invaluable in establishing whether it is possible to use this novel formulation to deliver combination drug therapy.
Principal Investigator: Professor Jayne Lawrence
Experimenter: Ms Yuvared Luangwitchajaroen
Experimenter: Ms Orathai Loruthai
DOI: 10.5286/ISIS.E.RB1510575
ISIS Experiment Number: RB1510575
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.61784935 | SANS2D | 17 June 2018 | Download |
| 10.5286/ISIS.E.61003026 | SANS2D | 17 June 2018 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jayne Lawrence et al; (2015): Nanosuspsomicroemulsions: nanosuspension stabilty, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510575
Data is released under the CC-BY-4.0 license.
