ISIS Neutron and Muon Source Data Journal

Proteins of Different Size and Globular Stability Adsorbed at Oil/Water Interfaces Studied by Neutron Reflection

Abstract: In this work we explore how to use neutron reflection to study protein adsorption at the oil/water interface. Inter is preferred because we have built technical capability on this instrument. Our specific aims are to (a) determine the actual thickness and volume fraction of globular lysozyme and (b) the effect of pH on the interfacial distribution. The results will enable us to compare the extent of proteins distributed into the oil region between lysozyme and large but less stable BSA at the interface. BSA has a distinct segment distribution in the oil region. The results from lysozyme will enable us to answer if this structural feature is unique to BSA as it contains regions for the delivery of fatty acids and lipids.

Principal Investigator: Professor Jian Lu
Experimenter: Dr Mario Campana
Experimenter: Dr John Webster
Experimenter: Mr Zhiming Lu
Experimenter: Mr Ruiheng Li

DOI: 10.5286/ISIS.E.RB1510071

ISIS Experiment Number: RB1510071

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Jian Lu et al; (2015): Proteins of Different Size and Globular Stability Adsorbed at Oil/Water Interfaces Studied by Neutron Reflection, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510071

Data is released under the CC-BY-4.0 license.