ISIS Neutron and Muon Source Data Journal

Binding Particles with Proteins at Interfaces

Abstract: Understanding and controlling the interaction of nanoparticles with biomaterials is key to alleviation of concerns about nanotoxicity. This knowledge can also be used to design ways to retain defined structures as required for nanofabrication using self-assembled particles. Studies of the simplest model systems are an initial key step. The present proposal is to use neutron reflection and off-specular scattering to observe the organisation of polystyrene latex particles on a protein layer. Moringa oleifera seed protein binds strongly and irreversibly to silica and at macroscopic interfaces such as those on large silicon crystals. The protein also binds to latex particles and these processes are important in understanding water purification using the protein as flocculent. The attractive interaction and binding can also provide a means to lock particles in particular structures.

Principal Investigator: Professor Adrian Rennie
Experimenter: Dr Majority Habauka Kwaambwa
Experimenter: Miss Shirin Nouhi
Experimenter: Dr Maja Hellsing

DOI: 10.5286/ISIS.E.RB1510461

ISIS Experiment Number: RB1510461

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Adrian Rennie et al; (2015): Binding Particles with Proteins at Interfaces, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510461

Data is released under the CC-BY-4.0 license.