ISIS Neutron and Muon Source Data Journal

Adsorption of nanodics (stabilised by sytrene-maleic anhydride derived copolymers) at the solid liquid interface

Abstract: Nanodiscs are self-assembled structures that consist of a bilayer of phospholipids controlled in diameter by a polymer or protein belt. We have already shown that such discs stabilised by the negatively charged poly (styrene-alt-maleic acid) (PSMA) will adsorb at the silicon-water interface when a lipid monolayer is present, but not on the bare silicon surface. Here we propose to repeat these measurements using a new polymer to stabilise the discs. This polymer, poly (styrene-co-maleimide) (PSMI) which is positively charged also forms discs, but in a different pH range to PSMA. This change is expected to modify the behaviour of adsorption, particularly on the bare silicon substrate and also allows the potential to remove the polymer after disc adsorption by simply modifying the pH and so destabilising the discs. This may offer a new method of making floating bilayers.

Principal Investigator: Dr Thomas Arnold
Experimenter: Ms Cecilia Tognoloni
Experimenter: Dr Stephen Hall
Experimenter: Professor Karen Edler
Experimenter: Dr Rob Barker

DOI: 10.5286/ISIS.E.RB1510346

ISIS Experiment Number: RB1510346

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Thomas Arnold et al; (2015): Adsorption of nanodics (stabilised by sytrene-maleic anhydride derived copolymers) at the solid liquid interface, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510346

Data is released under the CC-BY-4.0 license.