ISIS Neutron and Muon Source Data Journal

Drug solvation in amphiphilic solutions: understanding how small molecules cross the blood brain barrier

Abstract: Understanding how drugs interact with physiologically relevant environments is crucial for the future of effective drug design. An important class of potential drugs are central nervous system (CNS) drugs which need to cross the blood brain barrier (BBB) in order function. In the current work, we propose to investigate the solvation structure of drugs which cross the BBB in model environments which mimic the hydrophobic/hydrophilic interface of the BBB.

Principal Investigator: Dr Sylvia McLain
Experimenter: Miss Luxmmi Varathan
Experimenter: Dr Luis Carlos Pardo-Soto
Experimenter: Dr Sam Callear [Deactivated]
Experimenter: Mr Andrew Johnston
Experimenter: Dr Ric Gillams
Local Contact: Dr Silvia Imberti
Experimenter: Dr Richard Gillams

DOI: 10.5286/ISIS.E.RB1510104

ISIS Experiment Number: RB1510104

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Sylvia McLain et al; (2015): Drug solvation in amphiphilic solutions: understanding how small molecules cross the blood brain barrier, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510104

Data is released under the CC-BY-4.0 license.