ISIS Neutron and Muon Source Data Journal

Investigating the structural effects of bioactivity enhancements in doped hydroxyapatite.

Abstract: We wish to gain a deeper understanding of where dopant cations and anions reside in hydroxyapatite (HA). We will substitute Sr, Si, 11B and S into the HA structure and determine which sites in the unit cell each dopant preferentially occupies. Data such as shifts in interatomic distances or distortions to PO43- tetrahedral would also be useful. Such information cannot be obtained by simple XRD analysis (figure 1). However, by understanding how the charge and ionic radius of dopants ions dictates where they reside in mono-substituted HAs, we believe we can more quickly tailor novel substituted HAs to deliver a specific type of bioactivity behaviour. This increased understanding allows for improved experimental design and research efficiency when developing next generation bioceramics for applications in orthopaedic fields.

Principal Investigator: Professor David Grant
Experimenter: Dr Emma Barney
Experimenter: Mr Ben McCarthy

DOI: 10.5286/ISIS.E.RB1510415

ISIS Experiment Number: RB1510415

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor David Grant et al; (2015): Investigating the structural effects of bioactivity enhancements in doped hydroxyapatite., STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510415

Data is released under the CC-BY-4.0 license.