ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Dynamics of Phospholipid Based Vesicles: Effect of Addition of Salicylate Drugs and Amyloid Beta Peptides
Abstract: Structure and functions of cell membrane are susceptible to alterations as a consequence of interactions with chemical species. The objective of the proposed experiment is to study the effect of addition of salicylate drugs and amyloid beta (ABeta) peptide on the dynamics of phospholipid based uni-lamellar vesicles using quasi-elastic neutron scattering study. ABeta peptide plays a critical role in proliferation of Alzheimer¿s disease and salicylate drugs are the main ingredients in aspirin that is used widely in medications as an analgesic to relieve pain and reduce fever. This user proposal will help us to understand the interaction of these additives with lipid bilayer and its correlation with the microstructure of the vesicles.
Principal Investigator: Dr Veerendra K Sharma
Experimenter: Dr Volker S Urban
Experimenter: Dr Eugene Mamontov
Local Contact: Dr Victoria Garcia Sakai
DOI: 10.5286/ISIS.E.RB1510226
ISIS Experiment Number: RB1510226
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.58446479 | IRIS | 06 April 2018 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Veerendra K Sharma et al; (2015): Dynamics of Phospholipid Based Vesicles: Effect of Addition of Salicylate Drugs and Amyloid Beta Peptides, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510226
Data is released under the CC-BY-4.0 license.
