ISIS Neutron and Muon Source Data Journal

Further SANS contrast measurements on important protein/DNA interactions from RCaH

Abstract: This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing productive relationship between the two facilities, coordinated by Dr. David Scott of the University of Nottingham funded by ISIS to sited in the RCaH 2 days a week.The systems understudy all form part of crystallographic studies as part of an MRC programme grant to Prof. Simon Phillips, the RCaH Director, and all are important in the fundamental processes of DNA repair, recombination and replication. Preliminary data is available from SAXS and analytical ultracentrifugation measurements showing that the systems are stable in D2O and monodisperse. Preliminary SANS data through SANSexpresses has shown that suitable concentration ranges are attainable for further SANS measurements.

Principal Investigator: Dr David Scott
Experimenter: Dr Marcus Edwards
Experimenter: Mr Matthew Lawes
Experimenter: Dr Tom Clarke
Experimenter: Dr Gaye White
Experimenter: Dr DENIS PTCHELKINE
Experimenter: Miss Nishtha Gulati
Experimenter: Mr Matthew Green
Experimenter: Dr Stephen Carr
Local Contact: Dr Sarah Rogers
Local Contact: Dr Richard Heenan

DOI: 10.5286/ISIS.E.RB1410350

ISIS Experiment Number: RB1410350

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr David Scott et al; (2015): Further SANS contrast measurements on important protein/DNA interactions from RCaH, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1410350

Data is released under the CC-BY-4.0 license.