ISIS Neutron and Muon Source Data Journal

Iron Oxide Nanoparticle Interactions with Lipid Bilayers in a Magnetic Field

Abstract: Iron oxide nanoparticles are one of the first nanomaterials to be approved for use in the body. However, research into particle binding and incorporation to, as well as destabilization of, lipid and cell membranes is in its infancy despite its importance. Here, we propose to study the structure and destabilisation of the lipid bilayer in contact with IONPs using neutron reflection. The use of a magnetic adsorbent allows us to study the effect of an increasing static magnetic field perpendicular to the interface to either attract or repel the adsorbent from the lipid bilayer. The effect of an induced localised heating of the bilayer with an oscillating magnetic field will also be studied.

Principal Investigator: Professor Martin Malmsten
Local Contact: Dr Jos Cooper
Experimenter: Dr Kathryn Browning
Experimenter: Dr Sara Malekkhaiat Häffner
Experimenter: Miss Randi Nordström

DOI: 10.5286/ISIS.E.RB1620225

ISIS Experiment Number: RB1620225

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Martin Malmsten et al; (2016): Iron Oxide Nanoparticle Interactions with Lipid Bilayers in a Magnetic Field, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1620225

Data is released under the CC-BY-4.0 license.