ISIS Neutron and Muon Source Data Journal

Study of self-organization of cationic pH- and thermo responsive copolymers with gradient composition in water

Abstract: The aim of our work is to study structural properties of supra-molecular assemblies formed in aqueous solutions of cationic pH- and thermo-sensitive block-gradient copolymers comprising one block of poly(dimethylaminoethyl acrylate) (DMAEA) and one or two terminal blocks with a gradient sequence of styrene (S) and DMAEA monomer units. We expect that because of the gradient sequence of the terminal blocks such copolymers are capable of reversible association giving rise to micellar-like aggregates in aqueous solutions as a function of both pH and temperature. The cationic charge of the PDMAEA blocks opens the perspective to use this smart copolymer nanostructures as non-viral vectors for genetic material.

Principal Investigator: Dr Elise Deniau
Experimenter: Miss Monika Holubova
Experimenter: Miss Maria Rabyk
Experimenter: Dr Petr Stepanek
Local Contact: Dr Steve King

DOI: 10.5286/ISIS.E.RB1610433

ISIS Experiment Number: RB1610433

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Elise Deniau et al; (2016): Study of self-organization of cationic pH- and thermo responsive copolymers with gradient composition in water, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1610433

Data is released under the CC-BY-4.0 license.