This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Biomolecular Cryoprotection in Deep Eutectic Solvents
Abstract: Protecting biomolecules, such as proteins and enzymes, from the effects of cooling and freezing is important for the storage and handling of pharmaceuticals. Deep eutectic solvents provide a possible alternative biocompatible solvent that will prevent degradation of these delicate molecules. We propose to study the temperature dependent structure of proteins in a variety of deep eutectic solvents. These structural studies will be combined with calorimetric data and SAXS data to understand the mechanism of biomolecular cryoprotection.
Principal Investigator: Dr Andrew Jackson
Experimenter: Professor Karen Edler
Experimenter: Dr Adrian Sanchez-Fernandez
Experimenter: Dr Thomas Arnold
Experimenter: Dr Oliver Hammond
Local Contact: Dr Sarah Rogers
Experimenter: Miss Sian Fussell
DOI: 10.5286/ISIS.E.RB1520285
ISIS Experiment Number: RB1520285
Part DOI | Instrument | Public release date | Download Link |
---|---|---|---|
10.5286/ISIS.E.73944917 | SANS2D | 02 March 2019 | Download |
10.5286/ISIS.E.73944977 | SANS2D | 26 February 2019 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Andrew Jackson et al; (2016): Biomolecular Cryoprotection in Deep Eutectic Solvents, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1520285
Data is released under the CC-BY-4.0 license.