ISIS Neutron and Muon Source Data Journal

This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.


Biomolecular Cryoprotection in Deep Eutectic Solvents

Abstract: Protecting biomolecules, such as proteins and enzymes, from the effects of cooling and freezing is important for the storage and handling of pharmaceuticals. Deep eutectic solvents provide a possible alternative biocompatible solvent that will prevent degradation of these delicate molecules. We propose to study the temperature dependent structure of proteins in a variety of deep eutectic solvents. These structural studies will be combined with calorimetric data and SAXS data to understand the mechanism of biomolecular cryoprotection.

Principal Investigator: Dr Andrew Jackson
Experimenter: Professor Karen Edler
Experimenter: Dr Adrian Sanchez-Fernandez
Experimenter: Dr Thomas Arnold
Experimenter: Dr Oliver Hammond
Local Contact: Dr Sarah Rogers
Experimenter: Miss Sian Fussell

DOI: 10.5286/ISIS.E.RB1520285

ISIS Experiment Number: RB1520285

Part DOI Instrument Public release date Download Link
10.5286/ISIS.E.73944917 SANS2D 02 March 2019 Download
10.5286/ISIS.E.73944977 SANS2D 26 February 2019 Download

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Andrew Jackson et al; (2016): Biomolecular Cryoprotection in Deep Eutectic Solvents, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1520285

Data is released under the CC-BY-4.0 license.



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