This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Effects of Ionic liquids on the Dynamical and Phase Behaviour of Phospholipid Membrane
Abstract: Ionic liquids (ILs) have attracted considerable interest as a promising “green” substitute for organic solvents. Although, toxicity of some ILs is a cause for concern, recent studies have shown that the toxic interactions of ILs toward biological systems can be quite useful, particularly for antimicrobial applications. 1-n- alkyl-3-methylimidazolium (Cnmim), a popular class of ILs, has been shown to be toxic toward several classes of aquatic species and organisms. Interactions of ILs with the cellular membrane play a major role towards toxicity as well as antimicrobial applications. The fundamental mechanisms underlying the interactions between ILs and cells are not well studied nor completely understood. Our aim is to investigate effects of Cnmim( n=4, 8, 10) on the dynamical and phase behaviour of phospholipid membrane and its correlation with the cation chain length of the ILs.
Principal Investigator: Dr Ramaprosad Mukhopadhyay
Experimenter: Dr Veerendra K Sharma
Experimenter: Dr Subhankur Mitra
Experimenter: Dr Victoria Garcia Sakai
DOI: 10.5286/ISIS.E.RB1768020
ISIS Experiment Number: RB1768020
Part DOI | Instrument | Public release date | Download Link |
---|---|---|---|
10.5286/ISIS.E.87840357 | IRIS | 28 November 2020 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
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Dr Ramaprosad Mukhopadhyay et al; (2017): Effects of Ionic liquids on the Dynamical and Phase Behaviour of Phospholipid Membrane, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1768020
Data is released under the CC-BY-4.0 license.