ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Lipid dynamics in raft domains and effect of an oxidized bilayer component on their formation
Abstract: Lipid oxidation is linked to many adverse health effects. In this proposal we will use QENS in combination with contrast variation as a non-invasive method to detect and characterize the presence and size of microdomains formed in vesicles of biologically relevant lipids as a function of oxidized lipid levels and temperature. The domain forming lipid mixture system to be used in the present study will be composed of a saturated phospholipid, DPPC, an unsaturated phospholipid, POPC, and cholesterol (Chol) where a portion of the POPC is systematically replaced with the oxidized version of POPC, POnPC.
Principal Investigator: Dr Fabrizia Foglia
Experimenter: Professor Jayne Lawrence
Experimenter: Dr Dave Barlow
Experimenter: Dr Victoria Garcia Sakai
Experimenter: Dr Katherine Thompson
Experimenter: Miss Neelam Jhalley
Experimenter: Dr Delaram Ahmadi
DOI: 10.5286/ISIS.E.RB1720338
ISIS Experiment Number: RB1720338
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.87839972 | IRIS | 04 December 2020 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Dr Fabrizia Foglia et al; (2017): Lipid dynamics in raft domains and effect of an oxidized bilayer component on their formation , STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1720338
Data is released under the CC-BY-4.0 license.
