ISIS Neutron and Muon Source Data Journal

Polymer Chain exchange mechanism of complex coacervate core micelles (C3Ms) - Anionic homopolymer

Abstract: Complex coacervates have been studied for a long time for their medical applications and unusualphysical-chemical properties: they are dense networks of poly-electrolytes, that dissolve instead offlocculating when exposed to high salt concentrations. Despite being dense, they are fullypermeable to water, yet they are capable of strongly binding heavy metal ions or large (bio-)molecules, making them useful as drug carriers. By modifying them to form micelles, the micellecores become small coacervate networks; Complex Coacervate Core Micelles (C3Ms). Unlikegels, they are dispersed into solution easily and have an enormous active surface area. The formand structure of C3Ms are quite well known, but the exchange mechanism of polymers betweenmicelles is unknown. By performing contrast decay time-resolved SANS, we will determine ifpolymers migrate separately or not.

Principal Investigator: Dr Wim Bouwman
Experimenter: Dr Ilja Voets
Local Contact: Dr Robert Dalgliesh
Experimenter: Dr Ad van Well
Experimenter: Professor Katia Pappas
Experimenter: Mr Jurrian Bakker

DOI: 10.5286/ISIS.E.RB1669003

ISIS Experiment Number: RB1669003

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Wim Bouwman et al; (2017): Polymer Chain exchange mechanism of complex coacervate core micelles (C3Ms) - Anionic homopolymer, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1669003

Data is released under the CC-BY-4.0 license.