ISIS Neutron and Muon Source Data Journal

Investigation of the interactions of perfluoroalkyl substances with model worm and plant biomembranes

Abstract: Perfluoroalkyl substances (PFASs) are fully fluorinated, stabile, and surface-active compounds. They contain both a hydrophobic fluorinated carbon chain and an ionizable hydrophilic functional group, and can interact with biological membranes through different pathways, such as adsorption, penetration and displacement. PFASs have been found to accumulate in organisms in the environment, but there is a lack of knowledge on the mechanisms behind the accumulation. This proposal aims to use neutron reflection to investigate the interactions of perfluorooctane sulfonate, perfluorononanoate and perfluorohexanoate with standard eukaryotic mimic biomembrane and compare with model plant membrane to elucidate the influence of different functional groups and chain lengths on the sorption/accumulation behavior at the two different types of membranes.

Principal Investigator: Dr Maja Hellsing
Experimenter: Miss Shirin Nouhi
Experimenter: Dr Sarah Josefsson
Experimenter: Mr Hugo de Campos Pereira
Experimenter: Professor Lutz Ahrens
Local Contact: Dr Arwel Hughes

DOI: 10.5286/ISIS.E.RB1510508

ISIS Experiment Number: RB1510508

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Maja Hellsing et al; (2016): Investigation of the interactions of perfluoroalkyl substances with model worm and plant biomembranes, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1510508

Data is released under the CC-BY-4.0 license.