ISIS Neutron and Muon Source Data Journal

Oil disperse phospholipid stabilised microemulsions prepared using non-aqueous polar solvent

Abstract: It is the aim of the proposal is to perform small angle neutron scattering (SANS) studies combined with contrast variation to determine the size and structure of the phospholipid-stabilised microemulsions prepared using a dispese phase of a pharmaceutically acceptable oil in a polar, non-aqueous solvent. Of particular interest is the effect of the structure of the polar, non-aqueous solvent on the size and structure of the resulting microemulsion. Due to refractive index matching of the various microemulsion components, it is not possible to determine size or shape using light scattering. Consequently neutron studies are essential to study microemulsion formation in these water-free systems. The current studies will inform the future development of these interesting and potentially important delivery systems.

Principal Investigator: Professor Jayne Lawrence
Experimenter: Ms Demi Pink
Local Contact: Dr Najet Mahmoudi
Experimenter: Miss Simona-Vyara Kolarova
Experimenter: Dr Delaram Ahmadi
Experimenter: Dr Dave Barlow
Experimenter: Dr Fabrizia Foglia

DOI: 10.5286/ISIS.E.RB1710350

ISIS Experiment Number: RB1710350

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Jayne Lawrence et al; (2017): Oil disperse phospholipid stabilised microemulsions prepared using non-aqueous polar solvent, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1710350

Data is released under the CC-BY-4.0 license.